Twist Bioscience Corp (TWST US)
TWST US$173.58
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Performance
Share price activity
- Last (Price)
- 173.58
- Change
- ▲ 13.73 (8.59)
- Bid / Ask
- 167.86 - 173.47
- Volume
- 925,923
- Turnover
- 73,854,991
- Open
- 160.44
- Day Range
- 159.50 - 178.23
- VWAP
- 173.14
- Prev Close
- 159.85
- Last Trade
- 28/10 4:00pm
Key information
- Sector
- Healthcare
- Shares Issued
- 62,707,424
- NTA/Share
- 6.22
- Last Dividend
- —
- Dividend Ex Date
- —
- Dividend Pay Date
- —
Current (USD) · FY2025
- Revenue
- 376.57
- EBITDA
- -63.46
- Profit
- -77.67
- Earnings Per Share (EPS)
- -1.30
- Dividend Per Share (DPS)
- —
- Yield %
- 0.00
- Market Cap
- 11,508.56
- Price to Earnings Ratio (P/E)
- -77.83
Estimates (USD) · FY2027
- Revenue
- 532.40
- EBITDA
- —
- Profit
- 3.40
- Earnings Per Share (EPS)
- -0.29
- Dividend Per Share (DPS)
- —
Quantitative rating
Overvalued
- Economic Moat
- None
- Financial Health
- Moderate
- Uncertainty
- High
Morningstar Quantitative Rating as of 28 OCT 2026.
Quantitative Equity Rating Methodology – view here
Fair value estimate
Five-star price 95.27 Fair value 129.16 One-star price 175.10
Morningstar Quantitative Rating as of 28 OCT 2026.
Quantitative valuation
- Fair Value
- 129.16
- Price / Fair Value
- 1.34
- Valuation
- Overvalued
- Uncertainty
- High
Morningstar Quantitative Rating as of 28 OCT 2026. The slider runs from the five-star price (95.27) to the one-star price (175.10).
| Ratios |
|---|
| Currency (Price/reporting): USD/USD |
| Exchange Rate: 1.0000 |
| Price - closing or last bid | 173.58 |
| Price - 12 month high | 219.00 |
| Price - 12 month low | 23.50 |
| Pricing date | 27 OCT 2026 |
| Volume - avg. trading volume for the last ten days | 2.18 |
| Market capitalization | 11,499.94 |
| 12 Month High price date | 6 OCT 2026 |
| 12 Month Low price date | 14 NOV 2025 |
| Volume - avg. trading volume for the last 3 months | 2.24 |
| Price - 1 Day % Change | 8.59% |
| Price - 13 week price percent change | 96.02% |
| Price - 26 week price percent change | 193.46% |
| Price - 5 Day % Change | 16.40% |
| Price - 52 week price percent change | 417.07% |
| Price - YTD price percent change | 439.91% |
| Price % Change Month To Date | -3.35% |
| EPS excluding extraordinary items - most recent fiscal year | -1.300 |
| EPS excluding extraordinary items - trailing 12 month | -2.230 |
| EPS Normalized - most recent fiscal year | -1.094 |
| Revenue/share - most recent fiscal year | 6.296 |
| Revenue/share - trailing 12 month | 7.071 |
| Book value per share - most recent fiscal year | 7.801 |
| Book value per share - most recent quarter | 7.112 |
| Book value (tangible) per share - most recent fiscal year | 6.224 |
| Book value (tangible) per share - most recent quarter | 5.597 |
| Cash per share - most recent fiscal year | 3.019 |
| Cash per share - most recent quarter | 1.874 |
| Cash Flow per share - most recent fiscal year | -0.586 |
| Cash Flow per share - trailing 12 month | -0.742 |
| Dividend per share - most recent fiscal year | — |
| Dividends per share - trailing 12 month | 0.000 |
| EBITD per share - trailing 12 month | -1.940 |
| EPS Basic excluding extraordinary items - most recent fiscal year | -1.300 |
| EPS Basic excluding extraordinary items - trailing 12 month | -2.230 |
| EPS including extraordinary items - most recent fiscal year | -1.300 |
| EPS including extraordinary items - trailing 12 month | -2.230 |
| Free Cash Flow per share - trailing 12 month | -1.398 |
| P/E excluding extraordinary items, most recent fiscal year | — |
| P/E Normalized, most recent fiscal year | — |
| Price to sales - most recent fiscal year | 24.53 |
| Price to Tangible Book - most fiscal year | 30.99 |
| Price to Free Cash Flow per Share - most recent fiscal year | — |
| Price to Cash Flow per share - trailing 12 month | — |
| Price to Book - most recent fiscal year | 24.39 |
| P/E excluding extraordinary items high, trailing 12 months | — |
| P/E excluding extraordinary items low, trailing 12 months | — |
| Net Debt, LFI | -73.25 |
| Net Debt, LFY | -156.86 |
| Dividend Yield - 5 Year Average | — |
| Dividend Yield - indicated annual dividend divided by closing price | — |
| Current Dividend Yield - Common Stock Primary Issue, LTM | 0.00% |
| Free Cash Flow - most recent fiscal year | -84.58 |
| LT debt/equity - most recent fiscal year | 13.06% |
| Payout ratio - most recent fiscal year | — |
| Total debt/total equity - most recent fiscal year | 15.98% |
| LT debt/equity - most recent quarter | 19.06% |
| Total debt/total equity - most recent quarter | 21.00% |
| Free Cash Flow - trailing 12 month | -85.36 |
| Payout ratio - trailing 12 month | — |
| Revenue - most recent fiscal year | 376.57 |
| Revenue - trailing 12 month | 431.80 |
| EBITD - most recent fiscal year | -63.46 |
| EBITD - trailing 12 month | -118.48 |
| Earnings before taxes - most recent fiscal year | -76.95 |
| Earnings before taxes - trailing 12 month | -135.85 |
| Net Income available to common - most recent fiscal year | -77.67 |
| Net Income available to common - trailing 12 months | -136.72 |
| Earnings before taxes Normalized - most recent fiscal year | -61.34 |
| Net Income Available to Common, Normalized - most recent fiscal year | — |
| Earnings per Share, Normalized, Excluding Extraordinary Items, Avg. Diluted Shares Outstanding, TTM | -1.28 |
| Net Profit Margin % - 1st historical fiscal year | -20.63% |
| Net Profit Margin % - trailing 12 month | -31.66% |
| Operating margin - 1st historical fiscal year | -36.18% |
| Operating margin - trailing 12 month | -31.91% |
| Pretax margin - trailing 12 month | -31.46% |
| Pretax margin - 1st historical fiscal year | -20.43% |
| Operating Margin - 5 year average | -82.99% |
| Pretax Margin - 5 year average | -79.70% |
| Free Operating Cash Flow/Revenue, 5 Year Average | -58.89% |
| Free Operating Cash Flow/Revenue, TTM | -19.77% |
| Net Profit Margin - 5 year average | -78.55% |
| Return on average assets - most recent fiscal year | -12.51% |
| Return on average assets - trailing 12 month | -20.89% |
| Return on average equity - most recent fiscal year | -16.74% |
| Return on average equity - trailing 12 month | -29.62% |
| Return on average assets - 5 year average | -22.73% |
| Return on average equity - 5 year average | -28.41% |
| Net Income/employee - most recent fiscal year | -79,336.06 |
| Revenue/employee - most recent fiscal year | 384,649.64 |
| Revenue growth rate, 5 year | 33.11% |
| EPS growth rate, 5 year | — |
| Growth rate% - dividend, 3 year | — |
| Revenue/share (5 yr growth) | 22.32% |
| Growth rate% - Revenue, 3 year | 22.76% |
| Growth rate% - EPS, 3 year | — |
| Book value per share growth rate, 5 year | 0.90% |
| Capital Spending growth rate, 5 year | 23.20% |
| Earnings Before Interest, Taxes, Depreciation & Amortization, 5 Year CAGR | — |
Financial forecast (USD, millions except per share)
| Actuals | Estimates | |||||||
| 2025 | 2026 | 2027 | 2028 | 2029 | ||||
| Estimate breakdown | ||||||||
Financials (USD, millions)
| Period end: | SEP 21 | SEP 22 | SEP 23 | SEP 24 | SEP 25 |
| Fiscal year: | 2021 | 2022 | 2023 | 2024 | 2025 |
| Period length: | 12 months | 12 months | 12 months | 12 months | 12 months |
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Business Summary
Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA onsilicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.