Taysha Gene Therapies (TSHA US)
TSHA US$4.24
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Performance
Share price activity
- Last (Price)
- 4.24
- Change
- ▼ -0.02 (-0.35)
- Bid / Ask
- 3.87 - 4.24
- Volume
- 902,714
- Turnover
- 1,828,924
- Open
- 4.24
- Day Range
- 4.15 - 4.27
- VWAP
- 4.23
- Prev Close
- 4.25
- Last Trade
- 28/10 4:00pm
Key information
- Sector
- Healthcare
- Shares Issued
- 325,833,545
- NTA/Share
- 0.87
- Last Dividend
- —
- Dividend Ex Date
- —
- Dividend Pay Date
- —
Current (USD) · FY2025
- Revenue
- 9.77
- EBITDA
- -117.01
- Profit
- -109.00
- Earnings Per Share (EPS)
- -0.34
- Dividend Per Share (DPS)
- —
- Yield %
- 0.00
- Market Cap
- 1,379.91
- Price to Earnings Ratio (P/E)
- -10.33
Estimates (USD) · FY2027
- Revenue
- 0.00
- EBITDA
- —
- Profit
- -203.70
- Earnings Per Share (EPS)
- -0.50
- Dividend Per Share (DPS)
- —
Quantitative rating
Undervalued
- Economic Moat
- None
- Financial Health
- Moderate
- Uncertainty
- Very High
Morningstar Quantitative Rating as of 23 OCT 2026.
Quantitative Equity Rating Methodology – view here
Fair value estimate
Five-star price 3.04 Fair value 6.10 One-star price 12.26
Morningstar Quantitative Rating as of 23 OCT 2026.
Quantitative valuation
- Fair Value
- 6.10
- Price / Fair Value
- 0.65
- Valuation
- Undervalued
- Uncertainty
- Very High
Morningstar Quantitative Rating as of 23 OCT 2026. The slider runs from the five-star price (3.04) to the one-star price (12.26).
| Ratios |
|---|
| Currency (Price/reporting): USD/USD |
| Exchange Rate: 1.0000 |
| Price - closing or last bid | 3.97 |
| Price - 12 month high | 7.30 |
| Price - 12 month low | 3.46 |
| Pricing date | 22 OCT 2026 |
| Volume - avg. trading volume for the last ten days | 4.98 |
| Market capitalization | 1,290.30 |
| 12 Month High price date | 6 MAY 2026 |
| 12 Month Low price date | 14 OCT 2026 |
| Volume - avg. trading volume for the last 3 months | 3.51 |
| Price - 1 Day % Change | -1.00% |
| Price - 13 week price percent change | -31.99% |
| Price - 26 week price percent change | -38.05% |
| Price - 5 Day % Change | 9.53% |
| Price - 52 week price percent change | -19.74% |
| Price - YTD price percent change | -29.95% |
| Price % Change Month To Date | -19.25% |
| EPS excluding extraordinary items - most recent fiscal year | -0.340 |
| EPS excluding extraordinary items - trailing 12 month | -0.410 |
| EPS Normalized - most recent fiscal year | -0.295 |
| Revenue/share - most recent fiscal year | 0.031 |
| Revenue/share - trailing 12 month | 0.015 |
| Book value per share - most recent fiscal year | 0.866 |
| Book value per share - most recent quarter | 1.190 |
| Book value (tangible) per share - most recent fiscal year | 0.866 |
| Book value (tangible) per share - most recent quarter | 1.190 |
| Cash per share - most recent fiscal year | 1.122 |
| Cash per share - most recent quarter | 1.400 |
| Cash Flow per share - most recent fiscal year | -0.274 |
| Cash Flow per share - trailing 12 month | -0.357 |
| Dividend per share - most recent fiscal year | — |
| Dividends per share - trailing 12 month | 0.000 |
| EBITD per share - trailing 12 month | -0.441 |
| EPS Basic excluding extraordinary items - most recent fiscal year | -0.340 |
| EPS Basic excluding extraordinary items - trailing 12 month | -0.410 |
| EPS including extraordinary items - most recent fiscal year | -0.340 |
| EPS including extraordinary items - trailing 12 month | -0.410 |
| Free Cash Flow per share - trailing 12 month | -0.358 |
| P/E excluding extraordinary items, most recent fiscal year | — |
| P/E Normalized, most recent fiscal year | — |
| Price to sales - most recent fiscal year | 261.18 |
| Price to Tangible Book - most fiscal year | 3.33 |
| Price to Free Cash Flow per Share - most recent fiscal year | — |
| Price to Cash Flow per share - trailing 12 month | — |
| Price to Book - most recent fiscal year | 3.33 |
| P/E excluding extraordinary items high, trailing 12 months | — |
| P/E excluding extraordinary items low, trailing 12 months | — |
| Net Debt, LFI | -398.69 |
| Net Debt, LFY | -249.62 |
| Dividend Yield - 5 Year Average | — |
| Dividend Yield - indicated annual dividend divided by closing price | — |
| Current Dividend Yield - Common Stock Primary Issue, LTM | 0.00% |
| Free Cash Flow - most recent fiscal year | -88.46 |
| LT debt/equity - most recent fiscal year | 27.65% |
| Payout ratio - most recent fiscal year | — |
| Total debt/total equity - most recent fiscal year | 28.41% |
| LT debt/equity - most recent quarter | 14.34% |
| Total debt/total equity - most recent quarter | 14.64% |
| Free Cash Flow - trailing 12 month | -129.65 |
| Payout ratio - trailing 12 month | — |
| Revenue - most recent fiscal year | 9.77 |
| Revenue - trailing 12 month | 5.49 |
| EBITD - most recent fiscal year | -117.01 |
| EBITD - trailing 12 month | -159.37 |
| Earnings before taxes - most recent fiscal year | -109.00 |
| Earnings before taxes - trailing 12 month | -149.63 |
| Net Income available to common - most recent fiscal year | -109.00 |
| Net Income available to common - trailing 12 months | -149.63 |
| Earnings before taxes Normalized - most recent fiscal year | -94.50 |
| Net Income Available to Common, Normalized - most recent fiscal year | — |
| Earnings per Share, Normalized, Excluding Extraordinary Items, Avg. Diluted Shares Outstanding, TTM | -0.37 |
| Net Profit Margin % - 1st historical fiscal year | -1,115.27% |
| Net Profit Margin % - trailing 12 month | -2,728.04% |
| Operating margin - 1st historical fiscal year | -1,130.65% |
| Operating margin - trailing 12 month | -2,854.91% |
| Pretax margin - trailing 12 month | -2,728.04% |
| Pretax margin - 1st historical fiscal year | -1,115.27% |
| Operating Margin - 5 year average | -1,917.28% |
| Pretax Margin - 5 year average | -2,386.05% |
| Free Operating Cash Flow/Revenue, 5 Year Average | -1,230.94% |
| Free Operating Cash Flow/Revenue, TTM | -2,363.68% |
| Net Profit Margin - 5 year average | -2,386.05% |
| Return on average assets - most recent fiscal year | -42.18% |
| Return on average assets - trailing 12 month | -42.41% |
| Return on average equity - most recent fiscal year | -64.78% |
| Return on average equity - trailing 12 month | -56.94% |
| Return on average assets - 5 year average | -73.52% |
| Return on average equity - 5 year average | -301.02% |
| Net Income/employee - most recent fiscal year | -1,100,959.60 |
| Revenue/employee - most recent fiscal year | 98,717.17 |
| Revenue growth rate, 5 year | — |
| EPS growth rate, 5 year | — |
| Growth rate% - dividend, 3 year | — |
| Revenue/share (5 yr growth) | — |
| Growth rate% - Revenue, 3 year | 57.49% |
| Growth rate% - EPS, 3 year | — |
| Book value per share growth rate, 5 year | -33.49% |
| Capital Spending growth rate, 5 year | -39.47% |
| Earnings Before Interest, Taxes, Depreciation & Amortization, 5 Year CAGR | — |
Financial forecast (USD, millions except per share)
| Actuals | Estimates | |||||||
| 2025 | 2026 | 2027 | 2028 | 2029 | ||||
| Estimate breakdown | ||||||||
Financials (USD, millions)
| Period end: | DEC 21 | DEC 22 | DEC 23 | DEC 24 | DEC 25 |
| Fiscal year: | 2021 | 2022 | 2023 | 2024 | 2025 |
| Period length: | 12 months | 12 months | 12 months | 12 months | 12 months |
Announcements
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Business Summary
Taysha Gene Therapies Inc is a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. The company's clinical program TSHA-102is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. The Company views its operations and manages its business as a single operating segment, the gene therapy segment, which is the business of developing AAV-based gene therapies for the treatment of rare monogenic diseases of the central nervous system.