Protagonist Therapeutics (PTGX US)
PTGX US$144.34
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Performance
Share price activity
- Last (Price)
- 144.34
- Change
- ▲ 2.20 (1.55)
- Bid / Ask
- 96.58 - 144.46
- Volume
- 142,937
- Turnover
- 16,547,085
- Open
- 144.03
- Day Range
- 143.68 - 146.25
- VWAP
- 144.41
- Prev Close
- 142.14
- Last Trade
- 29/10 4:00pm
Key information
- Sector
- Healthcare
- Shares Issued
- 64,708,285
- NTA/Share
- 9.82
- Last Dividend
- —
- Dividend Ex Date
- —
- Dividend Pay Date
- —
Current (USD) · FY2025
- Revenue
- 46.02
- EBITDA
- -156.82
- Profit
- -130.15
- Earnings Per Share (EPS)
- -2.05
- Dividend Per Share (DPS)
- —
- Yield %
- 0.00
- Market Cap
- 9,339.99
- Price to Earnings Ratio (P/E)
- 140.14
Estimates (USD) · FY2027
- Revenue
- 67.77
- EBITDA
- —
- Profit
- -185.27
- Earnings Per Share (EPS)
- -2.80
- Dividend Per Share (DPS)
- —
Quantitative rating
Overvalued
- Economic Moat
- Narrow
- Financial Health
- Strong
- Uncertainty
- High
Morningstar Quantitative Rating as of 28 OCT 2026.
Quantitative Equity Rating Methodology – view here
Fair value estimate
Five-star price 99.78 Fair value 126.18 One-star price 159.56
Morningstar Quantitative Rating as of 28 OCT 2026.
Quantitative valuation
- Fair Value
- 126.18
- Price / Fair Value
- 1.13
- Valuation
- Overvalued
- Uncertainty
- High
Morningstar Quantitative Rating as of 28 OCT 2026. The slider runs from the five-star price (99.78) to the one-star price (159.56).
| Ratios |
|---|
| Currency (Price/reporting): USD/USD |
| Exchange Rate: 1.0000 |
| Price - closing or last bid | 142.14 |
| Price - 12 month high | 160.81 |
| Price - 12 month low | 74.95 |
| Pricing date | 27 OCT 2026 |
| Volume - avg. trading volume for the last ten days | 0.75 |
| Market capitalization | 9,197.64 |
| 12 Month High price date | 19 AUG 2026 |
| 12 Month Low price date | 28 OCT 2025 |
| Volume - avg. trading volume for the last 3 months | 0.65 |
| Price - 1 Day % Change | 0.72% |
| Price - 13 week price percent change | 3.87% |
| Price - 26 week price percent change | 40.44% |
| Price - 5 Day % Change | 2.94% |
| Price - 52 week price percent change | 81.05% |
| Price - YTD price percent change | 62.89% |
| Price % Change Month To Date | -0.21% |
| EPS excluding extraordinary items - most recent fiscal year | -2.050 |
| EPS excluding extraordinary items - trailing 12 month | 1.030 |
| EPS Normalized - most recent fiscal year | -1.479 |
| Revenue/share - most recent fiscal year | 0.724 |
| Revenue/share - trailing 12 month | 4.186 |
| Book value per share - most recent fiscal year | 9.823 |
| Book value per share - most recent quarter | 13.012 |
| Book value (tangible) per share - most recent fiscal year | 9.823 |
| Book value (tangible) per share - most recent quarter | 13.012 |
| Cash per share - most recent fiscal year | 2.052 |
| Cash per share - most recent quarter | 6.496 |
| Cash Flow per share - most recent fiscal year | -1.393 |
| Cash Flow per share - trailing 12 month | 1.937 |
| Dividend per share - most recent fiscal year | — |
| Dividends per share - trailing 12 month | 0.000 |
| EBITD per share - trailing 12 month | 0.887 |
| EPS Basic excluding extraordinary items - most recent fiscal year | -2.050 |
| EPS Basic excluding extraordinary items - trailing 12 month | 1.220 |
| EPS including extraordinary items - most recent fiscal year | -2.050 |
| EPS including extraordinary items - trailing 12 month | 1.230 |
| Free Cash Flow per share - trailing 12 month | 1.928 |
| P/E excluding extraordinary items, most recent fiscal year | 138.00 |
| P/E Normalized, most recent fiscal year | 80.90 |
| Price to sales - most recent fiscal year | 33.95 |
| Price to Tangible Book - most fiscal year | 10.92 |
| Price to Free Cash Flow per Share - most recent fiscal year | 73.72 |
| Price to Cash Flow per share - trailing 12 month | 73.38 |
| Price to Book - most recent fiscal year | 10.92 |
| P/E excluding extraordinary items high, trailing 12 months | 154.00 |
| P/E excluding extraordinary items low, trailing 12 months | 102.64 |
| Net Debt, LFI | -773.36 |
| Net Debt, LFY | -557.04 |
| Dividend Yield - 5 Year Average | — |
| Dividend Yield - indicated annual dividend divided by closing price | — |
| Current Dividend Yield - Common Stock Primary Issue, LTM | 0.00% |
| Free Cash Flow - most recent fiscal year | -90.13 |
| LT debt/equity - most recent fiscal year | 1.31% |
| Payout ratio - most recent fiscal year | — |
| Total debt/total equity - most recent fiscal year | 1.68% |
| LT debt/equity - most recent quarter | 0.81% |
| Total debt/total equity - most recent quarter | 1.10% |
| Free Cash Flow - trailing 12 month | 129.88 |
| Payout ratio - trailing 12 month | — |
| Revenue - most recent fiscal year | 46.02 |
| Revenue - trailing 12 month | 281.99 |
| EBITD - most recent fiscal year | -156.82 |
| EBITD - trailing 12 month | 59.76 |
| Earnings before taxes - most recent fiscal year | -129.31 |
| Earnings before taxes - trailing 12 month | 84.34 |
| Net Income available to common - most recent fiscal year | -130.15 |
| Net Income available to common - trailing 12 months | 82.91 |
| Earnings before taxes Normalized - most recent fiscal year | -83.34 |
| Net Income Available to Common, Normalized - most recent fiscal year | — |
| Earnings per Share, Normalized, Excluding Extraordinary Items, Avg. Diluted Shares Outstanding, TTM | 1.76 |
| Net Profit Margin % - 1st historical fiscal year | -282.83% |
| Net Profit Margin % - trailing 12 month | 29.40% |
| Operating margin - 1st historical fiscal year | -343.63% |
| Operating margin - trailing 12 month | 20.69% |
| Pretax margin - trailing 12 month | 29.91% |
| Pretax margin - 1st historical fiscal year | -281.01% |
| Operating Margin - 5 year average | -279.15% |
| Pretax Margin - 5 year average | -257.30% |
| Free Operating Cash Flow/Revenue, 5 Year Average | -835.65% |
| Free Operating Cash Flow/Revenue, TTM | 46.06% |
| Net Profit Margin - 5 year average | -257.86% |
| Return on average assets - most recent fiscal year | -18.20% |
| Return on average assets - trailing 12 month | 11.29% |
| Return on average equity - most recent fiscal year | -19.76% |
| Return on average equity - trailing 12 month | 12.10% |
| Return on average assets - 5 year average | -11.75% |
| Return on average equity - 5 year average | -13.62% |
| Net Income/employee - most recent fiscal year | -985,977.27 |
| Revenue/employee - most recent fiscal year | 348,606.06 |
| Revenue growth rate, 5 year | 9.96% |
| EPS growth rate, 5 year | — |
| Growth rate% - dividend, 3 year | — |
| Revenue/share (5 yr growth) | -2.75% |
| Growth rate% - Revenue, 3 year | 20.07% |
| Growth rate% - EPS, 3 year | — |
| Book value per share growth rate, 5 year | 8.98% |
| Capital Spending growth rate, 5 year | 27.55% |
| Earnings Before Interest, Taxes, Depreciation & Amortization, 5 Year CAGR | — |
Financial forecast (USD, millions except per share)
| Actuals | Estimates | |||||||
| 2025 | 2026 | 2027 | 2028 | 2029 | ||||
| Estimate breakdown | ||||||||
Financials (USD, millions)
| Period end: | DEC 21 | DEC 22 | DEC 23 | DEC 24 | DEC 25 |
| Fiscal year: | 2021 | 2022 | 2023 | 2024 | 2025 |
| Period length: | 12 months | 12 months | 12 months | 12 months | 12 months |
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Business Summary
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.